Accelerating Science: the Classical Mechanics Perspective

When thinking about enhancing R&D processes, Newton’s second law of motion provides the perfect framework.

Classical mechanics teaches us that putting a body into motion requires applying force. The resulting acceleration will be the sum of the forces applied to the body, divided by the body’s mass: a = F/m. So, if we want to accelerate R&D, what are the forces we need to consider? And, what is the mass?

In the lab, positive forces push the research forward. Humans design and run experiments. Machines process and measure samples. Computers run simulations and analyze data.

Frictional forces slow research down. There’s data that’s hard to find, clean, and analyze. Knowledge crucial to the business is trapped in people’s minds. There are long hand-offs between groups to analyze samples. Scientists and engineers with advanced degrees do menial work. There’s essential information shared in unstructured reports. All these things push back against researchers trying to do their job.

All of the steps in the R&D workflow make up the mass. It’s the sequence of operations required to go from a client’s request for a new material to samples sent back to them. It’s the iterative process needed to go from an active compound to a drug trial. These workflows require looking up historical data, exploring literature, and coordinating and communicating across multiple groups. Scientists must mix, shape, and test samples. They must inoculate, measure, and split cultures. Data must be recorded. Reports must be created. Workflows tend to grow in size and complexity. They get heavier and weigh down research.

In many labs, the acceleration is zero – not because work isn't being done, but simply because the positive forces equal the frictions listed above. Organizations can easily settle into a state of equilibrium where any work produced by humans in the lab is met with weighty and slow organizational processes. To combat this zero-sum-game, labs tend to explore ideas using an assembly line approach: research moves at a constant speed with a fixed throughput – slowly passing from one department to the next.

How to Accelerate

Given the previously defined formula for the acceleration of science workflows, a = F/m, there are only two variables that can be altered in an attempt to increase acceleration – the force and mass of R&D.

First, labs can accelerate by applying more positive force. People work harder and longer hours. Managers hire more staff and buy more machines to run more experiments. I.T. acquires more powerful computers. In our experience, pushing harder and spending more money is rarely a viable option.

Second, labs can accelerate by decreasing negative force. Reducing friction offers many possibilities. Individuals can embrace digital science and learn skills to automate repetitive analyses. Labs can invest in analytics-ready data: data that are searchable, accessible, and structured such that it makes sense to scientists. Scientists can use machine learning and deep learning to formalize and automate decision-making. Reducing friction has the lowest barrier to entry and the lowest risk. Everybody loves less friction. In addition to saving time and money, it creates margin. People need margin to innovate. Organizations need margin to implement more impactful changes.

Finally, changing workflowsreducing their massoften yields the most significant acceleration. A single person’s workflow can be streamlined, once again creating margin. But the biggest payoff comes from looking at the bigger picture: the workflow of an entire lab or business unit. That’s when it can be reconfigured and optimized using the latest technological advances. With a smaller mass, not only is it easier to accelerate, but it’s also easier to change direction. You get speed and agility.

Pragmatic Acceleration

Accelerating R&D starts with mapping out your existing workflows and their impediments. Once you have the map, you can make sound decisions about reducing friction or mass. Is there a particular step in a person’s workflow that is redundant, slow, and/or error-prone? Consider reducing the friction by training this individual to utilize digital tools for automation. Is there a workflow that involves multiple back-and-forth communications between departments to make final decisions on how to move forward in research? Evaluate the need for each of these communication efforts and explore batch processing requests or testing a new software solution to lessen the burden and hindrances for quickly moving forward by reducing the mass.

To truly accelerate science, consider the net forces acting on your workflow and determine how much mass your processes require. If you can adjust either or these in your favor, you’ll soon find a dramatic improvement in your R&D velocity.

About the Author

Alexandre Chabot-Leclerc, Ph.D., Vice President, Digital Transformation Solutions at Enthought, holds a doctoral degree in electrical engineering and a M.Sc. in acoustics engineering from the Technical University of Denmark and a B.Eng. in electrical engineering from the Université de Sherbrooke.

Share this article:

Related Content

Leveraging AI for More Efficient Research in BioPharma

In the rapidly-evolving landscape of drug discovery and development, traditional approaches to R&D in biopharma are no longer sufficient. Artificial intelligence (AI) continues to be a...

Read More

Utilizing LLMs Today in Industrial Materials and Chemical R&D

Leveraging large language models (LLMs) in materials science and chemical R&D isn't just a speculative venture for some AI future. There are two primary use...

Read More

Top 10 AI Concepts Every Scientific R&D Leader Should Know

R&D leaders and scientists need a working understanding of key AI concepts so they can more effectively develop future-forward data strategies and lead the charge...

Read More

Why A Data Fabric is Essential for Modern R&D

Scattered and siloed data is one of the top challenges slowing down scientific discovery and innovation today. What every R&D organization needs is a data...

Read More

Jupyter AI Magics Are Not ✨Magic✨

It doesn’t take ✨magic✨ to integrate ChatGPT into your Jupyter workflow. Integrating ChatGPT into your Jupyter workflow doesn’t have to be magic. New tools are…

Read More

Top 5 Takeaways from the American Chemical Society (ACS) 2023 Fall Meeting: R&D Data, Generative AI and More

By Mike Heiber, Ph.D., Materials Informatics Manager Enthought, Materials Science Solutions The American Chemical Society (ACS) is a premier scientific organization with members all over…

Read More

Real Scientists Make Their Own Tools

There’s a long history of scientists who built new tools to enable their discoveries. Tycho Brahe built a quadrant that allowed him to observe the…

Read More

How IT Contributes to Successful Science

With the increasing importance of AI and machine learning in science and engineering, it is critical that the leadership of R&D and IT groups at...

Read More

From Data to Discovery: Exploring the Potential of Generative Models in Materials Informatics Solutions

Generative models can be used in many more areas than just language generation, with one particularly promising area: molecule generation for chemical product development.

Read More

7 Pro-Tips for Scientists: Using LLMs to Write Code

Scientists gain superpowers when they learn to program. Programming makes answering whole classes of questions easy and new classes of questions become possible to answer….

Read More